Liver metastasis of uveal melanoma:mechanism and treatment strategy
10.3781/j.issn.1000-7431.2024.2312-0660
- VernacularTitle:葡萄膜黑色素瘤肝转移:机制及治疗策略
- Author:
Wangling ZHANG
1
;
Lianjun ZHAO
;
Yu REN
;
Zhengyun ZOU
Author Information
1. 南京大学医学院附属鼓楼医院综合肿瘤中心,江苏 南京 210008
- Publication Type:Journal Article
- Keywords:
Uveal melanoma;
Liver metastasis;
Mechanism;
Local treatment;
Systemic treatment
- From:
Tumor
2024;44(5):510-520
- CountryChina
- Language:Chinese
-
Abstract:
Uveal melanoma originates from the uveal tract and has a significant tendency to liver metastasis.Once metastasis occurs,the prognosis is poor.The current treatment options for uveal melanoma are liver-directed therapies including liver partial resection,ablation,isolated hepatic perfusion and percutaneous hepatic perfusion,hepatic artery infusion chemotherapy,transcatheter arterial chemoembolization,immune embolization,and radioembolization,and systemic treatment for metastatic uveal melanoma.This review discusses the pathogenesis of liver metastasis in uveal melanoma and reviews the current treatment options for uveal melanoma.
