Research progress of exosomes and the mechanism of urinary stone formation
10.3760/cma.j.cn112330-20250109-00013
- VernacularTitle:外泌体与泌尿系结石形成机制的研究进展
- Author:
Jihao CHEN
1
;
Chaoyue JI
;
Weiguo HU
Author Information
1. 青海大学附属医院泌尿外科 青海大学研究生院，西宁 810000
- Publication Type:Journal Article
- Keywords:
Exosome;
Urolithiasis;
Macrophage;
Inflammation
- From:
Chinese Journal of Urology
2025;46(7):551-554
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are closely related to the occurrence and development of various diseases. Exosomes from different sources and the bioactive molecules they carry can participate in the formation process of urinary calculi through mechanisms such as regulating inflammatory responses，autophagy，and crystal nucleation. In addition，exosomes can also serve as delivery platforms for precise treatment of urinary calculi patients based on targeted markers，which has become a new hot spot in the research of the mechanism and treatment of urinary calculi in recent years. This article reviews the current research progress of exosomes in the formation mechanism of urinary calculi.
