A case-control study on the attention characteristics of patients with stable schizophrenia
10.3969/j.issn.1002-0152.2025.01.006
- VernacularTitle:稳定期精神分裂症患者注意力特点的病例对照研究
- Author:
Honglei YANG
1
;
Kang XIE
;
Qunshan WANG
;
Zhenyue LIU
;
Wenjia LIU
;
Xinyi GE
;
Xianyun LI
Author Information
1. 承德医学院研究生学院(承德 067000);北京回龙观医院临床三科
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Control group;
Case-control study;
Attention;
Attention network test paradigm;
At-tentional function;
Reaction time
- From:
Chinese Journal of Nervous and Mental Diseases
2025;51(1):32-37
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the attention characteristics of patients with stable schizophrenia.Methods Fifty-five stable schizophrenic patients and 55 healthy subjects were included in the study.The attention network test paradigm(ANT paradigm)was used to measure the attention of participants.The observed indexes included reaction time under four cues and three stimulus types and converted reaction time(alerting network,orienting network,and executive control network).Results Under different cue prompts and stimulus conditions,the reaction time of patients with stable-phase schizophrenia was higher than that of the control group(P<0.001).The alerting network[25.43(11.71,42.53)ms vs.39.32(27.46,51.98)ms,P=0.020]and executive control network[96.17(36.32,160.13)ms vs.44.43(18.52,89.73)ms,P<0.001]in the patient group were significantly lower than those in the control group,while there was no significant difference in the orienting network compared to the control group(P=0.136).Conclusion Patients with stable schizophrenia show significant impairment in the efficiency of the alerting and executive control networks,while the orienting network is not significantly impaired.
