Two case reports of pediatric urinary non-Hodgkin lymphoma
10.3760/cma.j.cn112330-20240921-00419
- VernacularTitle:儿童泌尿系非霍奇金淋巴瘤2例报告
- Author:
Haiyan LIANG
1
;
Hongcheng SONG
;
Xingfeng YAO
;
Bei WANG
;
Ning LI
;
Weiping ZHANG
;
Ning SUN
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院泌尿外科，北京 100045
- Publication Type:Journal Article
- Keywords:
Lymphoma, non-Hodgkin;
Children;
Single urinary tumor
- From:
Chinese Journal of Urology
2025;46(1):65-66
- CountryChina
- Language:Chinese
-
Abstract:
Pediatric urological non-Hodgkin lymphoma is relatively rare.When a single renal or ureteral tumor with multiple lymph node or bone metastases is present, it is very easy to be misdiagnosed as urinary tumor with metastasis, resulting in unnecessary radical nephrectomy. This paper reports two cases of non-Hodgkin lymphoma presenting with single urinary nodules. Case 1 was diagnosed with a 4.5cm tumor in the right kidney due to fever and fatigue. CT and PET-CT showed multiple bone destruction and lymph node metastasis. Renal biopsy was performed and ALK-positive anaplastic large cell lymphoma was diagnosed. Chemotherapy was effective for 6 months. Case 2 was diagnosed with left hydronephrosis due to intermittent low back pain for 2 weeks. Ultrasound examination revealed ureteral dilation with left hydronephrosis and low echo occupying of the lower ureter. The patient had sudden blurred vision before surgery. MRI examination revealed space occupying in the right optic nerve frame, and PET-CT found multiple bone, lymph nodes and nerve invasion. A lymph node biopsy was performed and Burkitt lymphoma was diagnosed. After 6 months of chemotherapy and radiotherapy, the tumor shrank significantly.
