Mechanism of electromagnetic neuromodulation technology in the treatment of spinal cord injury: a review
10.3760/cma.j.cn501098-20250225-00104
- VernacularTitle:电、磁神经调控技术在脊髓损伤治疗中的作用机制研究进展
- Author:
Yuan LIU
1
;
Baorong HE
1
Author Information
1. 西安交通大学附属红会医院脊柱外科，西安 710054
- Publication Type:Journal Article
- Keywords:
Spinal cord injuries;
Transcranial magnetic stimulation;
Neuromodulation
- From:
Chinese Journal of Trauma
2025;41(9):903-911
- CountryChina
- Language:Chinese
-
Abstract:
Spinal cord injury is a debilitating neurological condition associated with a high of disability rate, leading to impairments in motor, sensory, and autonomic functions. Current early interventions such as decompression and pharmacological treatments show limited efficacy, often resulting in lifelong deficits in sensory, motor, and other functions, which impose a significant burden on patients, their families, and the society. Recently, electromagnetic neuromodulation has emerged as a promising biomedical technology encompassing a variety of invasive and non-invasive techniques such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and epidural electrical stimulation (EES) that effectively promote neurological recovery in patients with spinal cord injury. However, research on electromagnetic neuromodulation in improving functional impairments after spinal cord injury remains limited, with still uncertain clinical outcomes, necessitating further investigation to clarify its underlying mechanisms. To this end, the authors reviewed recent advances in the mechanistic understanding of electromagnetic neuromodulation in the treatment of spinal cord injury, focusing on pain control, motor function recovery, blood pressure regulation, urogenital function improvement, alleviation of respiratory dysfunction, and reduction of limb spasticity, aiming to provide a reference for the clinical application and future development of electromagnetic neuromodulation technology.
