Clinical value of ductoscopy,mammography,and high-frequency color Doppler ultrasonography in diagnosis of nipple bloody discharge combined with intraductal space occupying lesions
- VernacularTitle:乳管镜、乳腺钼靶、高频彩色多普勒超声对乳头血性溢液合并乳管内占位性病变的诊断价值
- Author:
Xiancheng AI
1
;
Zhihao YU
;
Xiangyu XU
Author Information
- Publication Type:Journal Article
- Keywords: ductoscopy; nipple bloody discharge; mammography; diagnostic value; high-frequency color Doppler ultrasonography; intraductal space occupying lesions
- From: China Journal of Endoscopy 2025;31(2):55-62
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the clinical significance of ductoscopy,mammography,and high-frequency color Doppler ultrasonography in diagnosis of nipple bloody discharge combined with intraductal space occupying lesions.Methods The medical records of 198 patients with nipple bloody discharge combined with intraductal space occupying lesions who underwent surgical treatment from January 2023 to December 2023 were retrospectively analyzed,all the subjects were examined by ductoscopy,mammography and high-frequency color Doppler ultrasonography before operation.The results of postoperative pathology were used as the gold standard to compare and evaluate the efficacy of single and combined use of the above three methods in the diagnosis of nipple bloody discharge combined with intraductal space occupying lesions.Results The results of postoperative pathological diagnosis showed that 152 cases of intraductal benign lesions were intraductal papilloma of the breast.There were 46 malignant lesions,of which 25 were intraductal carcinoma and 21 were invasive ductal carcinoma.The detection rates of nipple bloody discharge combined with intraductal space occupying lesions were 95.45%,81.31%,84.85%and 97.47%,respectively,by ductoscopy,mammography,high-frequency color Doppler ultrasonography and combined examination.Among them,the detection rate of ductoscopy and combined examination were significantly higher than that of mammography and high-frequency color Doppler ultrasonography(P<0.05),there was no significant difference between the detection rate of ductoscopy and combined examination(P>0.05),and there was no significant difference between the detection rate of mammography and high-frequency color Doppler ultrasonography(P>0.05).The sensitivity,specificity,and accuracy of diagnosing nipple bloody discharge combined with intraductal space occupying lesions using ductoscopy were 91.30%,97.20%,and 95.77%,respectively.The above indicators of mammography were 65.00%,94.21%,and 86.96%,respectively.The above indicators of high-frequency color Doppler ultrasonography were 70.73%,96.06%,and 89.88%,respectively.The above indicators of combination of the three methods were 95.65%,97.28%,and 96.89%,respectively.The sensitivity and accuracy of the combined examination of the three methods and the use of ductoscopy alone for the diagnosis of nipple bloody discharge combined with intraductal space occupying lesions were significantly higher than those of mammography and high-frequency color Doppler ultrasonography(P<0.05).However,there was no significant difference between mammography and high-frequency color Doppler ultrasonography(P>0.05),and there was also no significant difference between the combined examination of the three methods and the use of ductoscopy alone(P>0.05).There was no significant difference in diagnostic specificity among the four groups(P>0.05).Conclusion The diagnostic sensitivity and accuracy of ductoscopy for nipple bloody discharge combined with intraductal space occupying lesions are significantly higher than those of mammography and high-frequency color Doppler ultrasonography.The combined examination of the three can improve diagnostic efficiency to a certain extent,but the effect is limited.
