Efficacy and safety of intravascular lithotripsy in interventional treatment of calcified lesions in patients with acute and chronic coronary syndromes
10.3969/j.issn.1004-8812.2024.12.003
- VernacularTitle:经皮冠状动脉腔内冲击波球囊导管成形术在急性和慢性冠状动脉综合征患者钙化病变介入治疗中的有效性及安全性比较
- Author:
Hai-quan LI
1
;
Gai-gai MA
1
;
Xiao-jun LIU
1
;
Dan SU
1
;
Ya-rui LÜ
1
;
Xin-hong WANG
1
;
Zhen-hua HAN
1
;
Jie DENG
1
Author Information
1. 西安交通大学第二附属医院心内科,陕西西安 710004
- Publication Type:Journal Article
- Keywords:
Coronary artery calcification;
Intravascular lithotripsy;
Acute coronary syndrome;
Chronic coronary syndrome
- From:
Chinese Journal of Interventional Cardiology
2024;32(12):676-682
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of intravascular lithotripsy(IVL)in the treatment of coronary artery calcification in patients with acute coronary syndrome(ACS)and chronic coronary syndrome(CCS).Methods In a retrospective study,patients with coronary artery calcified lesions who underwent IVL treatment at the Department of Cardiology,Second Affiliated Hospital of Xi'an Jiaotong University between February 2023 and June 2024 were enrolled.Among them,22 patients in ACS group and 25 patients in CCS group.The differences in baseline data,complication,clinical success rate and major cardiovascular adverse events(MACE)in patients followed one month after the procedure were compared between the two groups.Results In the ACS group,21 stent implantations were successful(95.5％success rate),while in the CCS group,25 cases were successful(100.0％success rate),showing no statistically significant difference between the two groups(P=0.468).There was one case of intraoperative IVL balloon rupture in the ACS group(1/22;4.5％),while in the CCS group,three cases were observed(3/25;12.0％).Additionally,one case in the ACS group(1/22;4.5％)with slow blood flow after IVL calcification modification.No instances of IVL-related vessel dissection or target vessel rupture occurred between the two groups,and there was no statistically significant difference in intraoperative complications(all P＞0.05).There was no significant difference in the MACE(9.1％vs.4.0％,P=0.593)between the two groups for follow up of one month.Conclusions The technique of IVL is a safe and effective treatment option for patients with ACS or CCS who have coronary artery calcification lesions.
