Study on the Relationship between Systemic Immune-Inflammation Index,Platelet to Lymphocyte Ratio and Short-term Prognosis in Patients with Traumatic Cerebral Hemorrhage
10.13241/j.cnki.pmb.2025.14.010
- VernacularTitle:系统免疫炎症指数、血小板与淋巴细胞比值与创伤性脑出血患者短期预后的关系研究
- Author:
Gang WANG
1
;
Huan WANG
1
;
Fei GAO
1
Author Information
1. 沈阳医学院附属中心医院神经外二科 辽宁沈阳 110024
- Publication Type:Journal Article
- Keywords:
Traumatic cerebral hemorrhage;
Systemic immune-inflammation index;
Platelet to lymphocyte ratio;
Short-term prognosis
- From:
Progress in Modern Biomedicine
2025;25(14):2322-2328,2298
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between systemic immune-inflammation index(SII),platelet to lymphocyte ratio(PLR)and short-term prognosis in patients with traumatic cerebral hemorrhage.Methods:142 patients with traumatic cerebral hemorrhage who were admitted to our hospital from August 2021 to August 2024 were selected,they were divided into survival group and death group based on their prognosis.General information of patients with traumatic cerebral hemorrhage were collected,the general information,SII,and PLR levels at preoperative and 1 d,3 d postoperative between survival group and death group were compared.Influencing factors were analyzed by COX risk proportional regression model.Predictive value was analyzed by draw receiver operating characteristic(ROC)curves.Results:During 3-month follow up,there were 108 cases survived and 34 cases died,with a mortality rate of 23.94％.There were significant differences between the survival group and the death group in terms of midline shift,Glasgow Coma Scale(GCS)at 3 d postoperative,and National Institutes of Health Stroke Scale(NIHSS)at 3 d postoperative(P＜0.05).The SII and PLR of the death group at 1 d,3 d postoperative were significantly higher than those preoperative,and the SII and PLR of the death group at 1 d,3 d postoperative were significantly higher than those of the survival group(P＜0.05).COX regression analysis results showed that,NIHSS score at 3 d postoperative,SII at 1 d postoperative,SII at 3 d postoperative,PLR at 1 d postoperative,and PLR at 3 d postoperative elevation were independent risk factors for poor short-term prognosis in patients with traumatic cerebral hemorrhage(P＞0.05).ROC curve results showed that,the area under the curve(AUC)for predicting short-term poor prognosis in patients with traumatic cerebral hemorrhage using SII and PLR at 1 d postoperative was 0.743(0.685-0.802)and 0.718(0.650-0.786),respectively.The combined detection of the two predicted the AUC was 0.832(0.783-0.881).The AUC for predicting short-term poor prognosis in patients with traumatic cerebral hemorrhage using SII and PLR at 3 d postoperative was 0.797(0.743-0.851)and 0.755(0.699-0.812),respectively.The AUC for the combined prediction of the two was 0.866(0.825-0.906).The AUC for the combined detection of SII and PLR at 3 d postoperative was greater than that for the combined detection of SII and PLR at 1 d postoperative(P＜0.05).Conclusion:The SII and PLR levels in patients with traumatic cerebral hemorrhage are elevated,and their elevation is a risk factor for short-term poor prognosis in patients with traumatic cerebral hemorrhage.The combined detection of the two has a high predictive power for short-term poor prognosis in patients with traumatic cerebral hemorrhage.
