Research Advances in the Relationship Between Nonalcoholic Fatty Liver Disease and Cardiovascular-related Metabolic Diseases
10.3969/j.issn.1000-3614.2024.12.015
- VernacularTitle:非酒精性脂肪性肝病与心血管代谢疾病关系的研究进展
- Author:
Yongxiang CAI
1
;
Huihui HUANG
;
Huan DU
;
Long ZHOU
;
Jianhong TAO
Author Information
1. 电子科技大学医学院,成都 610054
- Publication Type:Journal Article
- Keywords:
non-alcoholic fatty liver disease;
atherosclerotic cardiovascular disease;
dyslipidemia;
diabetes;
hypertension
- From:
Chinese Circulation Journal
2024;39(12):1244-1248
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease,with a prevalence of about 29.2％ in China.A large number of clinical studies have shown that NAFLD is closely related to cardiovascular-related metabolic diseases such as obesity,dyslipidemia,diabetes mellitus,hypertension,etc.,and NAFLD is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD),and cardiovascular disease is the leading cause of death in patients with NAFLD.This article reviews the relationship between NAFLD and metabolic dysfunction-associated fatty liver disease (MAFLD) with ASCVD and related metabolic diseases,and discusses the related pathophysiological mechanisms such as insulin resistance,oxidative stress,and inflammation,aiming to provide practical recommendations for reducing the risk of NAFLD-associated cardiovascular disease.
