Characteristics of time-domain and time-frequency of Chinese word-picture matching task-related electroenceph-alogram in patients with post-stroke aphasia
10.3969/j.issn.1006-9771.2025.08.011
- VernacularTitle:卒中后失语患者汉语词图匹配任务态脑电的时域及时频特征
- Author:
Zihan ZHANG
1
;
Jinzhi GUAN
;
Xing HUANG
;
Li ZHOU
;
Yaxuan ZHANG
;
Mengyuan ZHANG
;
Jingling CHANG
Author Information
1. 北京中医药大学东直门医院,北京市 100070
- Publication Type:Journal Article
- Keywords:
post-stroke aphasia;
Chinese word-picture matching task;
electroencephalography;
event-related potential
- From:
Chinese Journal of Rehabilitation Theory and Practice
2025;31(8):947-957
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore characteristics of time-domain and time-frequency of task-related electroencephalogram(EEG)in patients with post-stroke aphasia(PSA).Methods From January,2018 to December,2021,18 PSA patients(PSA group)were recruited from Dongzhimen Hospi-tal,Beijing University of Chinese Medicine,and nine healthy subjects(control group)were recruited with matched gender,age and education level.EEG data based on the Chinese word-picture matching task were col-lected,and the average amplitude of N400 and event-related synchronization(ERS)/desynchronization(ERD)were analyzed.The PSA group was assessed with Chinese Rehabilitation Research Center Aphasia Examination(CRRCAE).Results The effect of N400 was significant on left frontal,central frontal,right frontal,left central and central areas.The average amplitude of N400 was higher on the frontal area in PSA group than in the control group,and it was low-er on right temporal-parietal area.For word-picture mismatching,average amplitude of N400 at FPZ was moder-ately correlated with auditory comprehension(r=0.483,P<0.05),the average amplitude of N400 at T8 was moderately correlated with repetition(r=0.584,P<0.05)and reading aloud(r=0.556,P<0.05),and the aver-age amplitude of N400 at P6 was moderately correlated with speaking(r=0.476,P<0.05)and reading(r=0.502,P<0.05).For word-picture matching,the average amplitude of N400 at P7 was moderately negatively cor-related with calculation(r=-0.481,P<0.05).Compared with the control group,the energy decreased in θ and αfrequency bands with absence of ERS in PSA group,and it increased in β frequency band with absence of ERD.Conclusion The activities of Chinese word-picture matching task-related EEG have been inhibited on right temporal-pa-rietal area for PSA patients,and it compensatively increases on frontal area,while the energy decreases in θ and αfrequency bands with ERS deficiency,and increases in β frequency band with ERD deficiency.
