Characteristics of pathological changes of the sclera in high myopia and rela-ted regulatory molecules
10.13389/j.cnki.rao.2025.0011
- VernacularTitle:高度近视巩膜病理改变特征及相关调控分子
- Author:
Dongmei YANG
1
;
Gang LIANG
;
Jun LI
;
Jing ZHAO
;
Zhi CHEN
;
Xingtao ZHOU
Author Information
1. 650000 云南省昆明市,云南大学附属医院
- Publication Type:Journal Article
- Keywords:
high myopia;
scleral lesion;
regulatory molecule
- From:
Recent Advances in Ophthalmology
2025;45(1):55-59
- CountryChina
- Language:Chinese
-
Abstract:
High myopia is a refractive abnormality characterized by excessive elongation of the eye axis.The sclera,as an important part of the eye axis regulation,plays a key role in the occurrence and development of high myopia.In this pa-per,based on the domestic and international articles,the pathological changes and related regulatory molecules of the scle-ra in high myopia were systematically summarized from the features of scleral lesions in high myopia and the gene regula-tion and signaling pathways affecting the ultrastructure and mechanical properties of the sclera,thus providing a theoretical basis for the study of the pathological mechanism of high myopia.
