Correlation between Edema Types and Adverse Pregnancy Outcomes in Pa-tients with Pre-eclampsia
- VernacularTitle:子痫前期患者水肿类型与妊娠不良结局的关系
- Author:
Huijing LI
1
;
Hongxu GU
1
;
Chunmei MI
1
Author Information
1. 中南大学湘雅三医院产科,湖南长沙 410013
- Publication Type:Journal Article
- Keywords:
Pre-eclampsia;
Edema;
Serous effusions;
Adverse pregnancy outcomes
- From:
Journal of Practical Obstetrics and Gynecology
2024;40(12):1019-1023
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the differences in adverse maternal-fetal outcomes among different types of edema in patients with pre-eclampsia(PE),and to explore the relationship between serous effusion and hypopro-teinemia in PE.Methods:We retrospectively collected clinical data of 120 patients with pre-eclampsia who were treated in the Third Xiangya Hospital of Central South University from January 2018 to November 2023.The pa-tients were divided into four groups based on the manifestation of edema:no edema(Type A),pure interstitial e-dema(Type B),pure cavity edema(pure serosal effusion,Type C),and mixed edema(both interstitial and cavity edema,Type D).Clinical and laboratory indicators as well as adverse maternal-fetal outcomes were analyzed a-mong these groups.Subsequently,the patients were further divided into three groups according to the amount of serous cavity effusion:PE without effusion,PE with mild effusion,and PE with moderate to severe effusion.Ad-verse maternal-fetal outcomes were compared among these three groups.Results:Patients in Type B had the highest proportion of hypoalbuminemia(P＜0.05).No statistically significant differences were found in serum albu-min levels,24-hour urinary protein quantification,blood pressure,or the proportion of hypoalbuminemia between patients in Type C and those in other edema types(P＞0.05).The incidence of adverse maternal-fetal outcomes was highest in Type D patients(P＜0.05),with HELLP syndrome and therapeutic premature delivery being the most common.When grouped by the amount of cavity effusion,PE patients with mild effusion had a higher inci-dence of adverse pregnancy outcomes than those without effusion(P＜0.05).Conclusions:Patients with serous cavity effusion,regardless of the effusion volume,have poor maternal-fetal outcomes and require clinical atten-tion.
