Clinical Study on the Treatment of Thin Endometrium of Kidney Deficiency and Blood Stasis Syndrome by Herb-Partitioned Moxibustion and Estradiol Valerate on the Navel and Estrogen
- VernacularTitle:隔药灸脐法联合戊酸雌二醇治疗肾虚血瘀型薄型子宫内膜的临床研究
- Author:
Hao SUN
1
;
Qingchang XIA
1
;
Zhibin DONG
1
;
Jiaze WANG
1
;
Yuxia MA
1
Author Information
- Publication Type:Journal Article
- Keywords: Thin endometrium; Kidney deficiency and blood stasis type; Herb-Partitioned Moxibustion on the Navel; Estradiol valerate; Clinical efficacy observation
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(2):539-544
- CountryChina
- Language:Chinese
- Abstract: Objective To observe the clinical efficacy of the combination of umbilical moxibustion and estradiol valerat in patients with thin endometrium.Methods A random number table was used to randomly divide 60 patients with thin endometrium of kidney deficiency and blood stasis type who met the inclusion criteria into an observation group of 30 cases and a control group of 30 cases.The control group took oral estradiol valerate tablets(DELPHARMLille S.A.S.,specification:1 mg/tablet),2 mg/day(bid),continuously for 21 days starting from the 5th day of the menstrual cycle;On the basis of the control group,the observation group was treated with herbal moxibustion on the navel,starting from the 7th day of the menstrual cycle,once a week,with an interval of 5-7 days.No treatment was given during the menstrual cycle,and both groups were treated continuously for three menstrual cycles.Observe the changes in endometrial thickness,Gonen classification of endometrium,uterine artery pulsatility index,resistance index,and traditional Chinese medicine clinical symptom score before and after treatment in two groups of patients.Results After treatment,the endometrial thickness of the two groups of patients increased(P<0.01),while the uterine artery pulsatility index and resistance index decreased compared to before(P<0.01).The total score of traditional Chinese medicine clinical symptoms decreased compared to before treatment(P<0.01).The above indicators were better in the observation group than in the control group(P<0.05).But the endometrial classification between the two groups of patients was no significant difference(P>0.05).Conclusion The combination of umbilical moxibustion and estradiol valerate can effectively promote uterine artery blood flow perfusion in patients with kidney deficiency and blood stasis type thin endometrium,reduce uterine artery pulsatility index and resistance index,increase the thickness of endometrium,and improve the clinical symptom score of traditional Chinese medicine.
