Application value of Jiedu Jiangtang Futan Decoction combined with acupuncture and moxibustion in treatment of patients with acute cerebral infarction complicated with diabetes(qi deficiency and blood stasis type)
10.3969/j.issn.1000-484X.2025.08.016
- VernacularTitle:解毒降糖复瘫汤联合针灸在脑梗死急性期合并糖尿病患者(气虚血瘀型)治疗中的应用价值
- Author:
Tianzhong PENG
1
;
Xuedi HUANG
;
Xingzhen LIN
;
Juan YUAN
;
Feng ZHOU
;
Siyan HU
;
Manhua ZHU
Author Information
1. 南昌市洪都中医院康复医学科,南昌 330008
- Publication Type:Journal Article
- Keywords:
Jiedu Jiangtang Futan Decoction;
Acupuncture and moxibustion;
Acute cerebral infarction complicated with dia-betes;
Qi deficiency and blood stasis type;
IL-6;
MMP-9;
VEGF;
Oxidative stress
- From:
Chinese Journal of Immunology
2025;41(8):1890-1894,1900
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application value of Jiedu Jiangtang Futan Decoction combined with acupuncture and moxibustion in the treatment of acute cerebral infarction patients with diabetes(qi deficiency and blood stasis type).Methods:All pa-tients with acute cerebral infarction complicated with diabetes(type of qi deficiency and blood stasis)were treated in Hongdu Tradi-tional Chinese Medicine Hospital from October 2020 to September 2022 and randomly divided into two groups,with 69 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with Jiedu Jiangtang Futan Decoction and acupuncture and moxibustion,and the efficacy was compared after two weeks of treatment.Results:Compared with before treatment,the serum levels of superoxide dismutase(SOD),vascular endothelial growth factor(VEGF)and brain-derived neurotrophic factor(BDNF)were increased in the two groups after treatment.The levels of serum matrix metalloproteinase-9(MMP-9),IL-6,fasting blood glucose(FBG),2-hour postprandial glucose(2 h PG)and glycated hemoglobin(HbA1c)were decreased.The Barthel index(BI)was increased,and the modified Rankin score(mRS)and National Institutes of Health Stroke Scale(NIHSS)were decreased(P<0.05).Compared with the control group,the levels of SOD,VEGF,BDNF and other indicators in the observation group were higher after treatment.The levels of MMP-9,IL-6,FBG,2 h PG and HbA1c were lower.BI was higher,mRS and NIHSS were lower,the difference were statistically significant(P<0.05).The total effective rate in the observation group was 94.20%(65/69),higher than 84.06%(58/69)in the control group(P<0.05).Conclusion:For patients with acute cerebral infarction complicated with diabetes(type of qi deficiency and blood stasis),the combination of Jiedu Jiangtang Futan Decoction and acupuncture and moxi-bustion treatment is helpful to promote blood supply to the brain,correct the imbalance of oxidative stress,regulate blood sugar level and improve clinical efficacy.
