Exploring the correlation between Qi deficiency and blood stasis and cellular scorching in cerebral ischemic stroke
10.3969/j.issn.1000-484X.2025.08.038
- VernacularTitle:气虚血瘀与细胞焦亡在缺血性脑卒中中的相关性探讨
- Author:
Zechao WANG
1
;
Yi ZHANG
1
;
Shuancheng ZHANG
1
;
Jing FANG
1
;
Xianming HOU
1
Author Information
1. 河北中医学院,河北省心脑血管病中医药防治研究重点实验室,石家庄 050091
- Publication Type:Journal Article
- Keywords:
Cerebral ischemic stroke;
Pyroptosis;
Qi deficiency and blood stasis;
Benefitting Qi and activating blood
- From:
Chinese Journal of Immunology
2025;41(8):2019-2024
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral ischemic stroke(CIS)is a serious health hazard with a high disability rate.Its pathogenesis is complex and not yet fully understood,and new effective treatments need to be explored.The newly discovered pyroptosis,which is regarded as a programmed cell death mode of inflammatory response,is involved in the pathogenesis of CIS.Inhibiting cellular scorch death during CIS and reducing the inflammatory response can effectively alleviate CIS brain injury.According to traditional Chinese medicine,defi-ciency of Qi and stasis of blood are the fundamental pathogenesis of CIS.The method of benefiting Qi and activating blood is the main principle for treating CIS.Therefore,in this paper,we link cell pyroptosis with Qi deficiency and blood stasis,review the progress of research on reducing brain tissue damage in CIS by inhibiting pyroptosis through the method of benefiting Qi and invigorating blood.
