Observation on the effects of hypesbaric oxygen combined with mecobalamin on electrophysiological changes in the treatment of carpal tunnel syndrome
10.3760/cma.j.issn.1009-6906.2016.05.015
- VernacularTitle:高压氧联合甲钴胺治疗腕管综合征的神经电生理疗效观察
- Author:
Lianhai ZHU
1
;
Li DING
;
Xinling LI
;
Zhenhui LU
;
Zhuomin LING
Author Information
1. 南通大学第二附属医院神经内科,江苏省南通,226001
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Carpal tunnel syndrome;
Mecobalamin;
Electrophysiology
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2016;23(5):390-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of hyperbaric oxygen (HBO) combined with mecobalamin on electrophysiological changes in the treatment of carpal tunnel syndrome (CTS).Methods Eighty-four cases of CTS were randomly divided into the mecobalamin group (n =28),the HBO group (n =28) and the HBO + mecobalamin group (n =28).The mecobalamin group was treated with mecobalamin,the HBO group received HBO therapy,and the latter group was given combined therapy,i.e.HBO plus mecobalamin.Both before and after treatment,all the patients received electrophysiological detection.Results After treatment,the median nerve sensory nerve conduction velocity (SCV),motor nerve conduction velocity (MCV),and the wave amplitude of the motor nerve compound muscle action potential (CMAP) of the combined group were all higher than those before treatment (P ＜ 0.05),while CMAP latency (BML) was lower than that before treatment (P ＜ 0.05).Following treatment,SCV of the Mecobalamin group was higher than that before treatment (P ＜ 0.05).SCV and MCV of the HBO group after treatment were higher than those before treatment (P ＜ 0.05).SCV and CMAP wave amplitude of the combined group significantly elevated as compared with that of the mecobalamin group (P ＜ 0.05),and SCV of the combined group was significantly higher than that of the HBO group (P ＜ 0.05).Conclusions HBO combined with mecobalamin could produce significant effects in the treatment of CTS.
