Correlation between CT imaging features and histopathology in isoattenuating and rim-enhancing pancreatic cancer
10.3969/j.issn.1002-1671.2025.08.016
- VernacularTitle:等强化与环形强化胰腺癌的CT影像征象与组织病理学的相关性研究
- Author:
Jing CHEN
1
;
Xiaoli SHUI
;
Can ZHANG
;
Tingwei QIN
Author Information
1. 三峡大学第一临床医学院 宜昌市中心人民医院放射科,湖北 宜昌 443000
- Publication Type:Journal Article
- Keywords:
pancreatic cancer;
heterogeneity;
computed tomography
- From:
Journal of Practical Radiology
2025;41(8):1329-1332
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between CT imaging features and histopathology invasive behaviors in isoat-tenuating and rim-enhancing pancreatic cancer.Methods A retrospective analysis was conducted on the CT imaging,clinical,and pathological data from 34 patients with atypical pancreatic cancer imaging appearances.All patients underwent surgical resection for diagnostic confirmation.Based on contrast attenuation,all cases were divided into isoattenuating group(13 cases)and rim-enhancing group(21 cases).The CT imaging and pathological characteristics of the two groups of lesions were analyzed.Results Significant differences were observed between the isoattenuating group and the rim-enhancing group in terms of lesion location,CT size,presence of necrosis or cystic changes,and common bile duct amputation/dilation.Pathological parameters,including pathological size,patho-logical grade,and T stage,also showed significant variation between the two groups(P＜0.05).No significant differences were found between the two groups in terms of gender,age,main pancreatic duct amputation/dilation,pancreatic parenchymal atrophy,vascular invasion,fat infiltration,nerve invasion,N stage,metastasis,and CA199 value(P＞0.05).Conclusion Isoattenuating pancreatic cancer and rim-enhancing pancreatic cancer,which display distinct contrast attenuation patterns,may exhibit different clinical and pathological characteristics,with potential implications for diagnostic and therapeutic strategies.
