The value of amide proton transfer imaging combined with diffusion weighted imaging in neurovascular invasion of stage T3/T4 rectal cancer
10.3969/j.issn.1002-1671.2025.08.015
- VernacularTitle:酰胺质子转移成像联合扩散加权成像对T3/T4期直肠癌神经脉管侵犯的价值探索
- Author:
Peiqi MA
1
;
Xiaoyan ZHANG
;
Xu LI
;
Bin PENG
;
Shubao SUN
;
Yushan YUAN
;
Xingwang WU
Author Information
1. 安徽医科大学第一附属医院放射科,安徽 合肥 230000;阜阳市人民医院影像中心,安徽 阜阳 236000
- Publication Type:Journal Article
- Keywords:
amide proton transfer imaging;
diffusion weighted imaging;
rectal cancer;
neurovascular invasion
- From:
Journal of Practical Radiology
2025;41(8):1324-1328
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of amide proton transfer(APT)imaging combined with diffusion weighted imaging(DWI)in the assessment of neurovascular invasion(NVI)of stage T3/T4 rectal cancer.Methods The clinical and MR imaging data of 46 patients with rectal cancer were analyzed retrospectively and divided into NVI positive group and NVI negative group according to the pathological results of NVI.The differences of APT values[maximum APT(APTmax)value,minimum APT(APTmin)value,mean APT(APTmean)value]and apparent diffusion coefficient(ADC)value between the two groups were compared,and the diagnostic efficiency was analyzed by receiver operating characteristic(ROC)curve.Results The APTmax and APTmean values in the NVI positive group were significantly higher than those in the NVI negative group,while the ADC value in the NVI positive group was significantly lower than that in the NVI negative group(P＜0.05).The area under the curve(AUC)of APTmax,APTmean and ADC values for NVI identification were 0.717,0.722 and 0.751,respectively.The AUC of the three indexes combined to identify NVI was 0.858.The combined AUC of the three indexes was larger than that of APTmax,APTmean and ADC alone(P＜0.05).Conclusion APT imaging combined with DWI has a high value in the evaluation of NVI of stage T3/T4 rectal cancer,which can provide guidance for clinical treatment.
