Therapeutic effects of hyperbaric oxygen combined with glucocorticoid on refractory idiopathic sudden deafness
10.3760/cma.j.issn.1009-6906.2014.04.002
- VernacularTitle:高压氧联合糖皮质激素治疗难治性突发性聋疗效观察
- Author:
Chen YANG
1
;
Yu ZHANG
1
;
Hang LI
1
;
Xiang'en MENG
1
;
Shuyi PAN
1
Author Information
1. 海军总医院全军高压氧治疗中心, 北京,100048
- Publication Type:Journal Article
- Keywords:
Sudden deafness;
Hyperbaric oxygen;
Glucocorticoid;
Combined therapy
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2014;21(4):219-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective Observe the therapeutic effects of hyperbaric oxygen (HB0) combined with glucocorticoid (GC) on refractory idiopathic sudden deafness.Methods Forty-two patients with sudden deafness (refractory idiopathic sudden deafness),who failed to recover after over one month of onset,were admitted into our Center from 2010 to 2013 for treatment with HBO combined with GC (referred to as the combined treatment group).Another 2 groups of patients with refractory idiopathic sudden deafness (each consisting of 32 patients),who were admitted into either our Center or the Department of Otorhinolaryngology of the Navy General Hospital and treated with simple HBO or GC,were used as controls.Through analyses of effective rates,cure rates and improvement rates in hearing,differences in therapeutic effects were compared between the patient group treated with HB0 combined with GC and the 2 control groups.Results The effective rate (59.52％) and improvement rate [(61.3 ± 4.7)％] for the combined treatment group were obviously higher than those of the simple HBO group[28.13％,(43.6 ± 5.5)％] and the simple hormone group [31.25％,(56.4 ± 4.1％].Conclusions The therapeutic effect of combined treatment with HBO + GC could produce good effects on refractory sudden deafness,however,adverse effects of hormones should be closely monitored in the process of the combined treatment.
