Analysis of coronary atherosclerosis characteristics and gender differences in patients with type 2 diabetes mellitus without cardiovascular symptoms by coronary computed tomography
10.3969/j.issn.1006-6187.2025.08.002
- VernacularTitle:应用冠状动脉计算机断层扫描分析无心血管疾病症状2型糖尿病患者冠状动脉粥样硬化特征及性别间差异的研究
- Author:
Linfen ZHAO
1
;
Fan ZHANG
;
Tao LI
;
Song XU
;
Jing ZHANG
;
Xinghua ZHANG
;
Li YANG
Author Information
1. 213161 常州,南京中医药大学武进附属医院放射科
- Publication Type:Journal Article
- Keywords:
Asymptomatic;
Diabetes mellitus,type 2;
Coronary atherosclerosis;
Coronary computed tomography angiography
- From:
Chinese Journal of Diabetes
2025;33(8):566-571
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics of coronary atherosclerosis(CAS)and the gender differences in type 2 diabetes mellitus(T2DM)patients without cardiovascular disease symptoms using coronary artery computed tomography(CCTA).Methods A total of 178 asymptomatic individuals with T2DM who underwent CCTA examination due to CAS risk factors were included in this analysis in 2019,and they were divided into male group(n=105)and female group(n=73)according to sex.The general data and biochemical indicators of patients of different genders were compared.Logistic regression was used to analyze the influencing factors of high-risk signs of CAS in patients with T2DM.The incidences of coronary artery involvement score(SIS)≥4 and segmental stenosis score(St.S)≥3 in male and female patients with different courses of DM were compared.Results The age and the proportion of hypertension in female patients with T2DM were higher than those in male patients(P<0.05),while the body mass index(BMI),smoking history,triglyceride(TG),total cholesterol(TC)/high-density lipoprotein cholesterol(HDL-C),and proportions of SIS≥4 were lower than those in male patients(P<0.05).Logistic regression analysis showed that the hypertension duration was an influencing factor for the occurrence of high-risk signs of CAS in patients with T2DM.The proportion of SIS≥4 in the female DM duration was higher than<5 years(P<0.05),and the proportion of SIS≥4 in>15 years was lower than<5 years(P<0.05).Conclusions The incidence of CAS high-risk signs in T2DM patients without cardiovascular symptoms is different between different sexes,the number of affected segments in women was related to the DM duration.
