Research Progress of Long-acting Injection for Children
10.3870/j.issn.1004-0781.2025.07.020
- VernacularTitle:儿童用长效注射剂研究进展
- Author:
Chenxi LI
1
;
Qingqing AN
;
Chaoxing HE
;
Huifeng ZHANG
;
Jia ZHANG
;
Bai XIANG
Author Information
1. 河北医科大学药学院,石家庄 050017
- Publication Type:Journal Article
- Keywords:
Long-acting injection;
Children;
Chemical coupling;
Fusion protein;
Monoclonal antibody;
Microsphere;
Nanocrystalline;
Hydrogels
- From:
Herald of Medicine
2025;44(7):1134-1141
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,there has been a gradual increase in the number of common diseases among children in China,especially younger children.Children are a unique population with distinct differences from adults,such as indications,dosage,accessories,and other characteristics,when it comes to using medication.Long-acting injections,in comparison to regular injections used for long-term treatment in children,can reduce sudden drug side effects and significantly decrease injection frequency.This greatly improves compliance among child patients and enhances clinical outcomes.Long-acting injections offer significant advantages for managing diseases in children.This paper reviews the progress made in basic research on long-acting injectable formulations for children based on interactions between drugs and materials.Additionally,potential future development directions are discussed to guide further advancements in long-acting injections specifically designed for children's needs.
