Multi-Parameter Cardiac Magnetic Resonance in Evaluating Ventricular Function Changes of Severe Alcohol Use Disorder Patients
10.3969/j.issn.1005-5185.2025.07.011
- VernacularTitle:心脏磁共振多参数评估重度酒精使用障碍患者心室功能改变的价值
- Author:
Jun CHENG
1
;
Shutian AN
;
Liangjun PANG
;
Zhen WANG
;
Yuguo LI
;
Yongqiang YU
;
Xiaohu LI
Author Information
1. 合肥市第四人民医院 安徽医科大学附属心理医院 安徽省精神卫生中心物质依赖科,安徽 合肥 230022
- Publication Type:Journal Article
- Keywords:
Alcohol use disorder;
Magnetic resonance imaging;
T1 mapping;
T2 mapping;
Ventricular function;
Extracellular volume fraction
- From:
Chinese Journal of Medical Imaging
2025;33(7):745-750
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To explore the application value of cardiac magnetic resonance(CMR)mapping and strain techniques in assessing ventricular function changes in patients with severe alcohol use disorder(AUD).Materials and Methods A retrospective analysis was conducted on 32 male patients with severe AUD as the study group in Hefei Fourth People's Hospital from January 2023 to April 2024,compared with 30 age-and gender-matched healthy subjects as the control group.Clinical data and CMR results were collected for all participants.CMR parameters included conventional functional parameters such as left and right ventricular ejection fraction,volume index and mass index;tissue characterization parameters such as Native T1,T2 mapping and extracellular volume fraction(ECV);and strain parameters including global longitudinal strain(GLS),global circumferential strain(GCS)and global radial strain(GRS)for both ventricles.The differences in the above indexes between the two groups were compared.Results The left ventricular end-diastolic volume index in the AUD group was significantly higher than in the control group(t=3.799,P<0.001).The left ventricular strain values(GLS,GCS,GRS)in the AUD group were significantly lower than those in the control group(t=4.459,4.435,-4.759,all P<0.001).The Native T1,T2 and ECV in the AUD group were significantly higher than those in the control group(t=6.301,5.650,7.069,all P<0.001).For the right ventricle,only right ventricular GLS and right ventricular GCS were significantly lower than in the control group(t=8.703,-2.814,both P<0.01).Conclusion CMR feature tracking technology can early identify ventricular function abnormalities in AUD patients.The increase in Native T1,T2 mapping and ECV suggests the presence of myocardial edema and fibrosis in AUD patients,which is closely related to left ventricular dysfunction.Multi-parameter CMR evaluation provides important diagnostic evidence for the early detection of cardiac involvement in severe AUD patients.
