Research progress on anti-tumor effect of monoterpene indole alkaloids in Uncariae Ramulus Cum Uncis
10.12173/j.issn.1005-0698.202403221
- VernacularTitle:钩藤中单萜吲哚类生物碱抗肿瘤作用的研究进展
- Author:
Dahai YU
1
;
Xue DONG
1
;
Lizhu ZHAO
1
Author Information
1. 哈尔滨商业大学药学院(哈尔滨 150078)
- Publication Type:Journal Article
- Keywords:
Uncariae Ramulus Cum Uncis;
Monoterpene indole alkaloids;
Anti-tumor;
Rhynchophylline;
Isorhynchophylline;
Hirsutine;
Hirsuteine;
Isocorynoxeine
- From:
Chinese Journal of Pharmacoepidemiology
2025;34(1):86-93
- CountryChina
- Language:Chinese
-
Abstract:
Uncariae Ramulus Cum Uncis has the effects of wind-extinguishing and convulsion resolving,clearing heat and liver smoothing It can be used to treat cancer,cardio-cerebrovascular diseases,neurodegenerative diseases,depression and other diseases.Studies have shown that Uncariae Ramulus Cum Uncis has significant anti-tumor activity and has inhibitory effects on many kinds of cancers,and monoterpene indole alkaloids are the main source of pharmacological effects of Uncariae Ramulus Cum Uncis.This paper reviewed the research related to the anti-tumor effect of monoterpene indole alkaloids from Uncariae Ramulus Cum Uncis in the last decade,and the anti-tumor mechanism was summarized to offer theoretical basis for the further study of monoterpene indole alkaloids in Uncariae Ramulus Cum Uncis.
