Research progress of ILC3s in tumor immunity
10.3969/j.issn.1000-484X.2025.09.040
- VernacularTitle:3型固有淋巴细胞在肿瘤免疫中的研究进展
- Author:
Xiangli PANG
1
;
Yan ZHANG
1
Author Information
1. 武汉大学人民医院妇1科,武汉 430000
- Publication Type:Journal Article
- Keywords:
ILC3s;
Tumor immunity;
Tumor mircoenvironment;
Immunoregulation
- From:
Chinese Journal of Immunology
2025;41(9):2302-2304,后插1-后插2
- CountryChina
- Language:Chinese
-
Abstract:
Cancer is a group of chronic diseases caused by a combination of genetic and environmental factors.Immune cells play a vital role in the regulation of tumor diseases.Recently,innate lymphoid cells(ILCs)have been found to have an important regu-latory role in the tumor microenvironment.ILCs are tissue resident immune cells located mainly in the mucosa and first barrier organs and have been extensively studied for defense against pathogenic invasion,lymphatic development and tissue repair.The role of ILCs in tumor immunity has received increasing attention in recent years.Among the various subpopulations of ILCs cells,the regulation of ILC3s in tumor immunity is the most controversial.Therefore,we summarized the role of ILC3s in tumor immunity by combining rele-vant studies on the involvement of ILC3s in tumor immune regulation in recent years.
