Research progress on the application and safety of botulinum toxin type A during pregnancy
10.12173/j.issn.1005-0698.202409081
- VernacularTitle:A型肉毒毒素在妊娠期的应用和安全性研究进展
- Author:
Yanan LIU
1
;
Hong CHENG
1
Author Information
1. 武汉大学中南医院药学部(武汉 430071)
- Publication Type:Journal Article
- Keywords:
Botulinum toxin type A;
Safety in pregnancy;
Birth defects;
Botulinum antitoxin
- From:
Chinese Journal of Pharmacoepidemiology
2025;34(2):216-223
- CountryChina
- Language:Chinese
-
Abstract:
Botulinum toxin type A has been widely used in disease treatment and cosmetic shaping.Women of childbearing age are the key population using botulinum toxin type A.Consultations about this drug are gradually increasing,but domestic reports on the application and safety during pregnancy are relatively rare.This study reviews the case reports of using botulinum toxin type A during pregnancy and before pregnancy,as well as pregnancy outcomes of botulinum toxin poisoning during pregnancy,discussing the safety and limitations of using botulinum toxin type A during pregnancy.The study showed when used in pregnancy at therapeutic doses,botulinum toxin type A has good effects on patients and can alleriate the patients'symptoms.Patients can avoid surgery or using drugs with lower safety during pregnancy.Exposure to botulinum toxin type A during pregnancy does not increase the incidence of fetal defects.Botulinum antitoxin should be given promptly to pregnant women with botulinum toxin type A poisoning.According to the current research data,it is suggested that botulinum toxin type A can be used as a therapeutic agent during pregnancy after fully informing patients of the risks of medication.
