Hashimoto's thyroiditis:Advances in immunological pathogenesis
10.3969/j.issn.1000-484X.2025.09.009
- VernacularTitle:桥本甲状腺炎:免疫学发病机制的进展
- Author:
Yi LI
1
;
Zimei TANG
1
;
Rong WANG
1
;
Jie MING
1
Author Information
1. 华中科技大学同济医学院附属协和医院甲状腺乳腺外科,武汉 430022
- Publication Type:Journal Article
- Keywords:
Hashimoto's thyroiditis;
Autoimmune diseases;
Pathogenesis;
Pathogenic factors
- From:
Chinese Journal of Immunology
2025;41(9):2098-2105
- CountryChina
- Language:Chinese
-
Abstract:
Hashimoto's thyroiditis(HT)is an organ-specific autoimmune disease characterized by a diffuse infiltration of lymphocytes in thyroid tissue.In recent years,incidence of HT has gradually increased and is a major cause of hypothyroidism in popu-lations in areas with adequate iodine intake,which can affect the quality of life of patients.A large number of studies have suggested that cellular and humoral immunity,related immune molecules and other factors affecting the immune response together constitute a complex network of immune regulation involved in the development of HT.With the development of immunology and other disciplines,the study of the immunological pathogenesis of HT is crucial to uncover its specific diagnostic criteria and treatment,and therefore,many researchers have focused on this issue and proposed new ideas.In this article,we review the advances of research on immunolog-ical pathogenesis of HT.
