Expression and significance of serum miR-27b-3p in patients with postmenopausal osteoporosis
10.3969/j.issn.1673-9701.2024.34.001
- VernacularTitle:绝经后骨质疏松患者血清miR-27b-3p的表达及意义
- Author:
Baisheng YE
1
;
Yifeng YUAN
;
Hang ZHOU
;
Zhen HUANG
;
Xudong HUANG
;
Jinkun LI
;
Xiaolin SHI
;
Binbin TANG
Author Information
1. 浙江中医药大学第二临床医学院,浙江杭州 310053
- Publication Type:Journal Article
- Keywords:
miR-27b-3p;
Bone metabolism;
Postmenopausal osteoporosis;
N-terminal propeptide of type Ⅰ procollagen;
C-terminal telopeptide of type Ⅰ collagen 1
- From:
China Modern Doctor
2024;62(34):1-5
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between serum miR-27b-3p and N-terminal propeptide of type Ⅰ procollagen (PINP) and C-terminal telopeptide of type Ⅰ collagen 1 (CTX-1) in postmenopausal women. Methods Forty-nine patients with postmenopausal osteoporosis treated in the Second Affiliated Hospital,Zhejiang Chinese Medical University from February 2022 to February 2023 were selected as study objects. They were divided into osteoporosis (OP) group (T≤-2.5SD,26 cases) and osteopenia (OPn) group (-2.5SD