Clinical Efficacy of Chaixia Sanjie Formula in Treating Pulmonary Nodules
10.11969/j.issn.1673-548X.2025.07.022
- VernacularTitle:柴夏散结方治疗肺结节的临床疗效研究
- Author:
Qinyan HONG
1
;
Mingsheng LV
;
Xinyi ZHANG
Author Information
1. 100700 北京中医药大学东直门医院;100029 北京中医药大学
- Publication Type:Journal Article
- Keywords:
Pulmonary nodules;
Traditional Chinese medicine;
Chaixia Sanjie formula;
Syndrome scores;
Retrospective study
- From:
Journal of Medical Research
2025;54(7):123-128,151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively analyze the clinical efficacy of the Chaixia Sanjie formula in treating pulmonary nodules.Methods Retrospective collection of 107 patients with pulmonary nodules and liver-qi stagnation syndrome who received the Chaixia Sanjie formula for 3months or more at Dongzhimen Hospital,Beijing University of Chinese Medicine,from January 2021 to June 2024 as the observation group.Another 107 patients with pulmonary nodules and liver-qi stagnation syndrome who did not receive traditional Chi-nese medicine(TCM)intervention during the same period were selected as the control group.Basic information,TCM syndromes,and the diameters of pulmonary nodules on chest HRCT at the first and last visit were collected.Changes in nodule diameter,TCM syndrome scores,and TCM therapeutic efficacy were compared between the two groups.Results Compared with the control group,the nodule di-ameter in the observation group was smaller and the difference was statistically significant(P＜0.05),and the proportion of nodule disap-pearance or reduction was higher in the observation group than in the control group,and the difference was statistically significant(P＜0.05).At the final diagnosis,the observation group showed a decrease in traditional Chinese medicine syndrome scores,including chest fullness,emotional instability,belching and bloating,rib pain,foreign body sensation in the throat,bitter mouth,lack of appetite,irreg-ular bowel movements,and sleep disorders,compared to the initial diagnosis and the control group,with statistical significance(P＜0.05).The effective rate of TCM syndrome improvement in the observation group was 88.8％.Conclusion The Chaixia Sanjie formula can reduce the diameter of pulmonary nodules to some extent and improve TCM syndromes in patients with pulmonary nodules.
