Research progress on the role of G-protein-coupled receptors in T lympho-cyte immunomodulation
10.12138/j.issn.1671-9638.20256437
- VernacularTitle:G蛋白偶联受体在T淋巴细胞免疫调节作用中的研究进展
- Author:
Chunyan CHANG
1
;
Yilin WANG
;
Yu PANG
;
Mengqiu GAO
Author Information
1. 首都医科大学附属北京胸科医院结核二区,北京 101149
- Publication Type:Journal Article
- Keywords:
G-protein-coupled receptors;
T lymphocytes;
immunity;
tuberculosis
- From:
Chinese Journal of Infection Control
2025;24(2):273-281
- CountryChina
- Language:Chinese
-
Abstract:
G-protein-coupled receptors(GPCRs)are a type of superfamily of transmembrane receptors,involved in multiple signaling pathways,and playing an important role in physiological processes such as cell migration and me-tabolism.T lymphocytes are important immune cells that participate in the inflammatory process and play an impor-tant role cellular immunity.To date,multiple GPCRs have been found to be expressed in T lymphocytes and partici-pate in T cell immunomodulatory processes.This paper reviews the role of GPCRs in T lymphocyte immunomodulation.