Predictive value of multimodal magnetic resonance imaging features for vascular invasion and prognosis in cervical cancer
10.3969/j.issn.1005-202X.2025.08.010
- VernacularTitle:多模态磁共振图像特征对宫颈癌脉管侵润及预后的预测价值
- Author:
Xiang WANG
1
;
Jinjun WANG
1
;
Xiaohong ZHANG
1
;
Yuquan JIAO
1
;
Jianfeng DING
1
Author Information
1. 山西医科大学附属运城市中心医院医学影像科,山西 运城 044000
- Publication Type:Journal Article
- Keywords:
multimodal;
magnetic resonance imaging;
cervical cancer;
vascular invasion;
prognosis
- From:
Chinese Journal of Medical Physics
2025;42(8):1047-1051
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of multimodal magnetic resonance imaging(MRI)features in predicting vascular invasion and prognosis in cervical cancer.Methods A total of 180 cervical cancer patients were included in this study.According to the postoperative vascular invasion status,patients were categorized into vascular invasion-positive group(n=61)and vascular invasion-negative group(n=119).All patients underwent comprehensive MRI protocols including diffusion-weighted imaging(DWI),diffusion tensor imaging(DTI),and dynamic contrast-enhanced MRI(DCE-MRI)scans to analyze intergroup differences in imaging parameters.The diagnostic efficacy of multimodal MRI(DWI,DTI,and DCE-MRI)in detecting vascular invasion and predicting prognosis was evaluated.Results Statistically significant differences in ADCDWI were observed between vascular invasion-positive group and vascular invasion-negative group(P<0.01).The vascular invasion-positive group exhibited significantly lower ADCDTI and FA as compared with vascular invasion-negative group,accompanied by elevated Ktrans,VE,and Kep(P<0.01).Compared with survival group,non-survivor group demonstrated higher ADCDWI,Ktrans,VE and Kep,alongside lower ADCDTI and FA.The sensitivity of multimodal MRI for vascular invasion detection and mortality prediction was higher than that of unimodal detection approaches.Conclusion Multimodal MRI features have significant predictive value for vascular invasion and prognosis in cervical cancer,serving as a critical foundation for clinical decision-making.
