Effect of Knee Osteochondral Defect Size on Stress Distributions in Surrounding Cartilage and Defect Rim
10.16156/j.1004-7220.2025.04.015
- VernacularTitle:膝关节骨软骨缺损尺寸对周围软骨和缺损边缘应力分布的影响
- Author:
Yun DOU
1
;
Xiangyun CHENG
1
;
Dong JIANG
1
Author Information
1. 北京大学第三医院运动医学科,北京 100191
- Publication Type:Journal Article
- Keywords:
knee joint;
osteochondral defect;
peak pressure;
stress concentration;
peak-to-rim distance
- From:
Journal of Medical Biomechanics
2025;40(4):902-907
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of single osteochondral defect of the knee on pressure distributions in weight-bearing area of the medial femoral condyle,and further evaluate changes of the location of peak pressure on the medial condyle with the defect size changing.Methods Ten fresh porcine knee joints were fixed in extension position.First,mechanical loads were applied to the medial compartment of the normal porcine knee joint to determine the maximum contact pressure area.Then,rounded osteochondral defects with different diameters(in depth of 9 mm)were drilled at this area,respectively.The 100,200,300 N axial compression loads were applied to the medial compartment of each knee joint,and the strength and location of the peak contact pressure during loading were recorded.Results The peak pressure increased with defect size increasing,and the phenomenon of stress concentration appeared.The peak pressure was significantly higher in the defect with diameter exceeding 8 mm than that in the non-defect knee.The peak pressure showed a similar tendency to move closer to the defect rim as the defect size increased(the distance between the peak pressure position and the defect rim,namely peak-to-rim distance,decreased).Conclusions In the single knee osteochondral defect model,when the diameter of the defect at the weight-bearing area was larger than 8 mm,the peak pressure on the uninjured site significantly increased,and the peak-to-rim distance significantly decreased,which implied 8 mm as a potential threshold for surgical intervention.
