Comparison of efficacy and safety of thulium laser-assisted and laparoscopic nephron-sparing surgery in the treatment of renal angiomyolipoma
10.3969/j.issn.1009-8291.2025.08.009
- VernacularTitle:铥激光辅助与传统腹腔镜保留肾单位手术治疗肾血管平滑肌脂肪瘤临床疗效及安全性比较("大家泌尿网"观看手术视频)
- Author:
Kai HUANG
1
;
Jingguang ZHANG
;
Biao CHEN
;
Zhou SHEN
Author Information
1. 蚌埠医科大学研究生院,安徽 蚌埠 233000;中国科学技术大学附属第一医院(安徽省立医院)泌尿外科,先导医学与前沿技术研究所,安徽 合肥 230001
- Publication Type:Journal Article
- Keywords:
thulium laser;
renal angiomyolipoma;
renal artery clamping;
nephron-sparing surgery;
laparoscope;
estimated glomerular filtration rate
- From:
Journal of Modern Urology
2025;30(8):685-688
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy and safety of thulium laser-assisted versus traditional laparoscopic nephron-sparing surgery for the treatment of exophytic renal angiomyolipoma(AML),so as to provide reference for the treatment selection of this disease.Methods The clinical data of 43 AML patients admitted to our hospital during Jan.2022 and Nov.2024 were retrospectively analyzed,including 10 cases in the thulium laser group and 33 cases in the traditional laparoscopic group.In the thulium laser group,renal artery clamping was not performed,while the traditional laparoscopic group underwent conventional renal artery clamping.The general and perioperative data of the two groups were compared.Results All 43 patients successfully underwent surgery,with postoperative pathological confirmation of AML and no severe complications.There were no statistically significant differences between the two groups in terms of operation time,intraoperative blood loss,hemoglobin decline on the first day postoperatively,catheter indwelling time,and postoperative hospital stay.The thulium laser group had shorter warm ischemia time[0 min vs.(21.88±3.84)min,P＜0.01]and less decline in estimated glomerular filtration rate(eGFR)3 months after operation[(0.62±2.42)mL/(min·1.73 m2)vs.(5.74±4.84)mL/(min·1.73 m2),P＜0.01]than the traditional laparoscopic group.During a follow-up of 4-34 months,no tumor recurrence was observed.Conclusion Thulium laser-assisted laparoscopic nephron-sparing surgery is safe and feasible in the treatment of exophytic renal AML without renal artery clamping,which may have promising advantages in the protection of renal function.
