Research progress on the phototherapy in vitiligo
10.3969/j.issn.1006-5725.2025.17.006
- VernacularTitle:光疗在白癜风治疗中的研究进展
- Author:
Rongyin GAO
1
;
Congchong WAN
;
Chuanwei YIN
;
Jin-peng LÜ
Author Information
1. 常州市第一人民医院药学部(江苏 常州 213000)
- Publication Type:Journal Article
- Keywords:
vitiligo;
phototherapy;
NB-UVB;
helium-neon laser;
blue light
- From:
The Journal of Practical Medicine
2025;41(17):2646-2652
- CountryChina
- Language:Chinese
-
Abstract:
Phototherapy plays a significant role in vitiligo treatment.Narrow-band ultraviolet B(NB-UVB)remains the first-line phototherapy for non-segmental vitiligo in clinical practice.In recent years,visible light has emerged as a novel therapeutic approach for vitiligo.Studies indicate that helium-neon laser demonstrates superior efficacy in segmental vitiligo,blue light is more effective for localized vitiligo,and NB-UVB is better suited for generalized or extensive vitiligo.Different phototherapy modalities exhibit distinct mechanisms of action,involving multiple biological proteins and signaling pathways in melanocyte activation and repigmentation.This review sum-marizes recent advances in phototherapy for vitiligo treatment.
