Insight into the grading of breast phyllodes tumors
10.3760/cma.j.cn112151-20241225-00871
- VernacularTitle:乳腺叶状肿瘤诊断分级的困惑和进展
- Author:
Yunfan WANG
1
;
Xue ZONG
;
Weicheng XUE
Author Information
1. 北京大学首钢医院病理科，北京 100144
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Diagnosis;
Malignant phyllodes tumor
- From:
Chinese Journal of Pathology
2025;54(3):219-223
- CountryChina
- Language:Chinese
-
Abstract:
Phyllodes tumors (PT) of the breast is a rare fibroepithelial tumor, which can be divided into benign, borderline and malignant pathological types according to its histological characteristics. Malignant phyllodes tumor (MPT) accounts for 10%-20% of PT and has the ability of local recurrence and distant metastasis. Therefore, accurate diagnosis and identification of MPT are particularly important for patients to obtain appropriate treatment at the initial diagnosis. At present, histological morphology is the only diagnostic basis for MPT. However, due to the fact that phyllode tumor itself is a continuous disease spectrum with overlapping histological features, and the diagnostic classification adopts many histological parameters and their evaluation is subjective, pathologists lack consistency in MPT grading, and the biological behavior of PT is not completely consistent. Therefore, the existing MPT classification standards are facing challenges, and the accurate and reproducible classification is worthy of further exploration.
