Epidemiological and clinical characteristics of Keshan disease current cases in Qingyang City, Gansu Province in 2022
10.3760/cma.j.cn231583-20240115-00015
- VernacularTitle:2022年甘肃省庆阳市克山病现患病例流行病学和临床特征分析
- Author:
Jing LUO
1
;
Yun WANG
;
Ping LI
;
Xiaoliang SUN
;
Huixin DENG
;
Qian YANG
;
Zhaoyan HU
;
Ying GAO
Author Information
1. 庆阳市疾病预防控制中心（市卫生监督所）地方病防制科，庆阳 745000
- Publication Type:Journal Article
- Keywords:
Keshan disease;
Distribution;
Condition;
Analysis
- From:
Chinese Journal of Endemiology
2024;43(12):968-971
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the epidemiological and clinical characteristics of Keshan disease current cases in Qingyang City, Gansu Province.Methods:Full coverage monitoring data of all Keshan disease affected villages in Qingyang City from January to December 2022 were collected from the database of the Qingyang City Center for Disease Prevention and Control. A retrospective analysis was conducted to analyze the epidemiological distribution and clinical manifestations (including electrocardiography, classification of cardiac function, chest X-ray, B-mode ultrasound of the heart, etc) of 132 current cases of Keshan disease.Results:Among the 132 current cases of Keshan disease, there were 5 cases of latent type and 127 cases of chronic type, and 25 new cases were identified in 2022; with a male-to-female ratio of 1.03 ∶ 1.00 (67 ∶ 65), a median age of 62 years (interquartile range of 12). The area with the highest number of current cases was Heshui County, with a Keshan disease incidence rate of 3.37/10 000; the lower areas were Xifeng District and Zhenyuan County, with a Keshan disease incidence rate of 0.08/10 000 and 0.03/10 000, respectively. The abnormal electrocardiogram of the current cases was mainly characterized by T-wave and/or ST-segment changes, with a total of 78 cases, accounting for 59.09% of the total cases. Heart function impairment (grade Ⅱ and above) was found in 124 cases, accounting for 93.94%. The results of B-mode ultrasound and chest X-ray examination showed that there were 107 cases of heart enlargement, accounting for 81.06% of the total cases.Conclusions:The Keshan disease current cases in Qingyang City are predominantly chronic in elderly, with a balanced gender distribution but regional distribution differences. Abnormal electrocardiogram is common in patients, and their cardiac function is often impaired. Given the persistent presence of pathogenic factors, continued monitoring is necessary to achieve early intervention and improve prognosis.
