Research progress on copper homeostasis imbalance and copper complexes in gy-necological tumors
10.13315/j.cnki.cjcep.2025.11.013
- VernacularTitle:铜稳态失衡及铜复合物在妇科肿瘤中的研究进展
- Author:
Zhensen WENG
1
;
Qian XU
;
Wei ZHANG
;
Chunji QUAN
Author Information
1. 海南医科大学第一临床医学院,海口 570100
- Publication Type:Journal Article
- Keywords:
gynecologic tumors;
copper homeostasis;
copper complexes;
anticancer mechanism;
research progress;
literature review
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(11):1492-1498
- CountryChina
- Language:Chinese
-
Abstract:
Copper is one of the essential elements in the human body,playing various physiological roles.Maintai-ning copper homeostasis is crucial for health.Recent researches have uncovered that copper homeostasis imbalance is closely associated with the occurrence,progression,prognosis,and drug resistance of gynecological malignancies.The employment of copper and its complexes in antitumor therapy has emerged as a promising novel approach,attracting considerable research attention.Based on the relationship between copper homeostasis imbalance and gynecological tumors,this paper provides a concise review of the current status and progress of copper and its complexes in the treat-ment of gynecological tumors.