Associations between prenatal environmental factors on attention deficit hyperactivity disorder in children
10.3969/j.issn.1000-6729.2025.12.05
- VernacularTitle:产前环境因素与儿童注意缺陷多动障碍的关联研究
- Author:
Ziqi YANG
1
;
Xinxin YUE
1
;
Lu LIU
1
;
Qiujin QIAN
1
;
Yufeng WANG
1
Author Information
1. 北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京 100083
- Publication Type:Journal Article
- Keywords:
attention deficit hyperactivity disorder(ADHD);
risk factors;
maternal stress during pregnan-cy;
maternal smoking during pregnancy;
preconception paternal alcohol consumption
- From:
Chinese Mental Health Journal
2025;39(12):1037-1042
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association between prenatal environmental factors and attention defi-cit hyperactivity disorder(ADHD)and its symptom severity in children.Methods:Based on the Diagnostic and Statistical Manual of Mental Disorders,Fourth Edition(DSM-Ⅳ)diagnosis criteria,1 156 children with ADHD and 289 normal control children were included in this study.ADHD diagnoses were established using the Clinical Diag-nostic Interview Scale,core symptoms were assessed with the ADHD Rating Scale,and information on prenatal ex-posures were collected via self-developed questionnaires.Results:Maternal stress during pregnancy was associated with increased risk factor of ADHD in children(OR=1.22,P＜0.01).Among children with ADHD,preconception paternal alcohol consumption was positively associated with hyperactivity/impulsivity symptoms(β=0.08,P＜0.05),and maternal smoking during pregnancy was positively associated with total symptoms(β=0.07-0.09,P＜0.05).Conclusion:Maternal stress during pregnancy may increase the risk factor of ADHD in children.Both pre-conception paternal alcohol consumption and maternal smoking during pregnancy may be associated with increased ADHD symptom severity in children.
