Application of Omics Technologies in the Study of Traditional Chinese Medicine's Anti-infective Properties
10.3870/j.issn.1004-0781.2025.06.013
- VernacularTitle:组学技术在中药抗感染研究中的应用
- Author:
Huaiyuan SUN
1
;
Wenyue LI
;
Jiajia FENG
;
Weihua KONG
;
Kun JIANG
;
Likai LIN
Author Information
1. 武汉大学医院管理研究所,武汉 430071
- Publication Type:Journal Article
- Keywords:
Anti-infective effect of traditional Chinese medicine;
Omics technology;
Anti-infective
- From:
Herald of Medicine
2025;44(6):917-923
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine(TCM)has been used for the control and prevention of infectious diseases for thousands of years.Due to its characteristics of multiple components and multiple targets,it shows promising therapeutic prospects in the field of anti-infection.Here,we provide a detailed introduction to the current application of various omics technologies,such as metabolomics,proteomics,genomics,and transcriptomics in the study of TCM's anti-infective properties.The application of omics technologies can help explore the active components and their targets in TCM that contribute to its anti-infective effects;elucidate the biosynthetic pathways of active components,aiding in the discovery of new active ingredients;and investigate the mechanisms by which TCM affects pathogenic microorganisms,as well as interpret the mechanisms of TCM's synergy with antibiotics.As more research findings are produced and validated,the role of TCM in addressing the global challenge of antimicrobial resistance will become increasingly prominent through the integration of multi-omics and multidisciplinary research methods in the future.
