Zebrafish applications in anti-tumor drug research and clinical studies
10.3969/j.issn.1005-4847.2025.04.010
- VernacularTitle:斑马鱼在抗肿瘤药物和临床研究中的应用
- Author:
Lin LI
1
;
Rongli QIU
;
Kaifeng WEI
;
Haibo CHENG
;
Dongdong SUN
Author Information
1. 南京中医药大学中医学院,南京 210023
- Publication Type:Journal Article
- Keywords:
zebrafish;
anti-tumor;
drug;
screening;
drug resistance;
clinic therapy
- From:
Acta Laboratorium Animalis Scientia Sinica
2025;33(4):561-566
- CountryChina
- Language:Chinese
-
Abstract:
Zebrafish is a relatively new experimental animal model with unique characteristics that enable its wide use in research on many human diseases.The exploration of anti-tumor drugs and other clinical treatments remain the focus of current research on cancer.Zebrafish characteristics,including rapid development,ease of observation,high genetic homology,and low-cost gene editing,make them highly useful for tumor research.By covering the applications of zebrafish in anti-tumor drug research and clinical studies,this review aims to provide valuable insights for the further utilization of zebrafish in cancer drug screening,assessment of drug activity and toxicity,and clinical research.