West China Hospital′s protocol for the diagnosis and treatment of prolonged disorders of consciousness secondary to severe traumatic brain injury
10.3760/cma.j.cn501098-20250406-00196
- VernacularTitle:重型创伤性脑损伤所致慢性意识障碍诊疗的华西医院经验
- Author:
Yikai YUAN
1
;
Tong SUN
;
Junwen GUAN
Author Information
1. 四川大学华西医院神经外科，成都 610041
- Publication Type:Journal Article
- Keywords:
Brain injuries;
Consciousness disorders;
Neuromodulation
- From:
Chinese Journal of Trauma
2025;41(8):721-727
- CountryChina
- Language:Chinese
-
Abstract:
Prolonged disorders of consciousness (pDoC) represent severe complications following severe traumatic brain injury, imposing substantial burden on both families and the society. Currently, the diagnosis and treatment of pDoC still face challenges, including insufficient assessment accuracy and limited efficacy of arousal therapies. On one hand, innovative approaches such as neuroimaging, electrophysiological techniques, and neuromodulation have provided new directions for the diagnosis and treatment of pDoC, yet standardized diagnostic and therapeutic protocols as well as large-scale clinical evidence remain lacking. On the other hand, standardized management of pDoC requires multidisciplinary collaboration, yet the limited number of specialized arousal centers in China hinders the provision of systematic therapy. The Department of Neurosurgery at West China Hospital, Sichuan University has established a comprehensive pDoC care system through a multidisciplinary team approach. To this end, the authors systematically summarized the clinical exploration and advancements in pDOC arousal therapy by West China Hospital′s neurosurgical team, aiming to provide valuable insights for domestic peers and jointly advance the optimization and advancement of pDoC diagnosis and treatment.
