Etiology and prognosis analysis of intracranial hemorrhage in children
10.3760/cma.j.cn431274-20240318-00448
- VernacularTitle:儿童颅内出血的病因及预后分析
- Author:
Ronghua ZHU
1
;
Qiuying SHEN
Author Information
1. 玉林市第一人民医院神经外科，玉林 537000
- Publication Type:Journal Article
- Keywords:
Intracranial hemorrhages;
Child
- From:
Journal of Chinese Physician
2025;27(4):573-577
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the etiology and prognosis of intracranial hemorrhage in children and provide a basis for the prevention of intracranial hemorrhage in children.Methods:A retrospective analysis was conducted on the clinical data of children with intracranial hemorrhage aged 29 days to 14 years admitted to the First People′s Hospital of Yulin from January 2012 to December 2022.Results:There were a total of 535 children with intracranial hemorrhage, including 355 boys and 180 girls. The high-incidence age ranged from 29 days to 1 year, with 235 cases (43.93%). The common causes of intracranial hemorrhage were as follows: falling from heights 27.48%(147/535), late-onset vitamin K deficiency 20.56%(110/535), and car accidents 9.53%(51/535). Spontaneous intracranial hemorrhage was more common in infants, while traumatic intracranial hemorrhage was more common in young children. The mortality rate of children with intracranial hemorrhage was 14.20%(69/486), and the disability rate was 14.81%(72/486). Univariate analysis showed that late-onset vitamin K deficiency, leukemia, flat fall, car accident, subdural hemorrhage, cerebral parenchymal hemorrhage, subarachnoid hemorrhage, and multi-site hemorrhage were associated with the poor prognosis (disability and death) of intracranial hemorrhage in children (all P<0.05). Multivariate analysis showed that late-onset vitamin K deficiency and cerebral parenchymal hemorrhage were independent risk factors for intracranial hemorrhage disability in children (all P<0.05); Leukemia and cerebral parenchymal hemorrhage are independent risk factors for intracranial hemorrhage death in children (all P<0.05). Conclusions:The incidence of intracranial hemorrhage in boys is higher than that in girls, with the highest incidence in infants aged 29 days to 1 year. Intracranial hemorrhage in children is commonly caused by falls from heights, late-onset vitamin K deficiency and car accidents. Late-onset vitamin K deficiency and cerebral parenchymal hemorrhage are independent risk factors for disability, while leukemia and cerebral parenchymal hemorrhage are independent risk factors for death. Preventing various causes of intracranial hemorrhage is an important measure to reduce intracranial hemorrhage in children.
