When portal hypertension does not result from liver cirrhosis: How to identify and optimize treatment?

VernacularTitle:当门静脉高压不源于肝硬化：如何识别与优化治疗？
Author: Siyu JIANG ¹ ; Shiyao CHEN
Author Information

1. 复旦大学附属中山医院消化科，上海　200032
Publication Type:Journal Article
Keywords: Portal hypertension; Stratified diagnosis and treatment
From: Journal of Chinese Physician 2025;27(4):481-485
CountryChina
Language:Chinese
Abstract: The etiology of non-cirrhotic portal hypertension (NCPH) is complex and there is a lack of a clear pathogenesis. Early diagnosis is difficult, which is an important clinical challenge. The diagnosis of NCPH requires a combination of clinical features, risk factors and auxiliary examinations. Pathological biopsy is the key to a confirmed diagnosis. The treatment of NCPH focuses on tracing the cause of the disease as the core and individualized management of the primary disease and complications. In the future, a stratified diagnosis and treatment system based on multi-omics needs to be constructed to optimize prognosis management, thereby improving the long-term prognosis of patients with NCPH.