Molecular characteristics and advances in drug therapy of ovarian clear cell carcinoma
10.3969/j.issn.1672-8467.2025.03.017
- VernacularTitle:卵巢透明细胞癌的分子特征和药物治疗进展
- Author:
Yue TAN
1
;
Yan XU
;
Zhi-ling ZHU
Author Information
1. 复旦大学附属妇产科医院妇科 上海 200011
- Publication Type:Journal Article
- Keywords:
ovarian clear cell carcinoma(OCCC);
molecular characteristics;
chemotherapy;
targeted therapy;
immunotherapy
- From:
Fudan University Journal of Medical Sciences
2025;52(3):450-457
- CountryChina
- Language:Chinese
-
Abstract:
Ovarian clear cell carcinoma(OCCC)typically exhibited high-grade atypia and aggressive chemotherapy resistance,leading to poor prognosis,necessitating continuous exploration of novel therapeutic approaches to enhance patient survival and quality of life.In recent years,with the in-depth study of the biological behavior and molecular characteristics of OCCC,unique molecular features of OCCC were discovered,making it a potential molecular target for personalized biotherapy,with the prospect of improving treatment efficacy and patient prognosis.An increasing number of clinical trials focused on exploring the driver mutations and molecular characteristics of recurrent OCCC in the hope of finding more precise and effective treatment modalities.This article provided a comprehensive review of the molecular characteristics of OCCC and advances in drug therapy.
