Clinical application of near infrared autofluorescence imaging combined with nano-carbon surgery to identify parathyroid glands
10.3760/cma.j.cn431274-20240706-01045
- VernacularTitle:近红外自体荧光显像联合纳米碳手术中识别甲状旁腺的临床应用
- Author:
Bofeng DUAN
1
;
Wei PENG
1
;
Fuyong QIAN
1
;
Zhifeng FAN
1
;
Yi XIE
1
;
Xiaoying FU
1
;
Wei ZHENG
1
Author Information
1. 深圳市第三人民医院（南方科技大学第二附属医院）甲乳外科，深圳 518112
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Parathyroid glands;
Near-infrared autofluorescence;
Nano-carbon
- From:
Journal of Chinese Physician
2025;27(3):408-410
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effect of near-infrared autofluorescence (NIRAF) imaging combined with nano-carbon in the identification of parathyroid gland.Methods:A total of 80 patients with thyroid cancer requiring bilateral thyroidectomy plus single/bilateral central area lymphatic dissection were prospectively enrolled in the Department of Thyroid and Breast Surgery of the Shenzhen Third People′s Hospital from January 2020 to June 2023. Two groups were divided in order of time of admission. In the combined group (40 cases), the parathyroid glands were identified by NIRAF+ nano-carbon negative imaging. The nano-carbon group (40 cases) was negatively developed with nano-carbon alone. The detection rate and accuracy of parathyroid gland and the changes of parathyroid hormone (1 d and 6 months after operation) were compared between the two groups.Results:There was no significant difference in the detection rate of parathyroid glands between the two groups ( P=0.65), and the accuracy rate in the combined group was higher than that in the nano-carbon group, the difference was statistically significant (χ 2=8.79, P=0.003). The level of parathyroid hormone in the combined group was higher than that in the nano-carbon group 1 day after surgery, and the difference was statistically significant ( Z=-1.19, P=0.03). There was no significant difference in parathyroid hormone levels between the two groups 6 months after operation ( P=0.18). Conclusions:NIRAF imaging combined with nano-carbon negative imaging can improve the accuracy of intraoperative parathyroid identification, and may reduce the incidence of temporary postoperative hypoparathyroidism.
