Research progress in the relationship between immune dysfunction and gut microbiota dysbiosis of idiopathic nephrotic syndrome in children
10.13431/j.cnki.immunol.j.20240111
- VernacularTitle:儿童特发性肾病综合征免疫功能障碍与肠道菌群失调的关系研究进展
- Author:
Yu ZHU
1
;
Jingjing WANG
;
Yueling ZHU
;
Yao ZHANG
Author Information
1. 310000 杭州,浙江大学医学院附属儿童医院国家儿童健康与疾病临床医学研究中心国家儿童区域医疗中心中医科
- Publication Type:Journal Article
- Keywords:
Idiopathic nephrotic syndrome;
Immune function;
Gut microbiota;
Children
- From:
Immunological Journal
2024;40(10):796-801
- CountryChina
- Language:Chinese
-
Abstract:
Idiopathic nephrotic syndrome(INS)in children is a type of primary glomerular disease caused by a variety of causes.Recent research has highlighted the pivotal roles of immune dysfunction and gut microbiota imbalance in its development.Regulatory T cell dysfunction is key in INS progression,and changes in gut microbiota composition and its metabolic byproducts are closely tied to immune system disruption.This study aims to perform a systematic review of the relationship between immune dysfunction and gut microbiota dysbiosis in INS children.
