Clinical Study on Qishao Huoxue Prescription for the Treatment of Lumbar Disc Herniation in Qi Stagnation and Blood Stasis Syndrome
10.19879/j.cnki.1005-5304.202412171
- VernacularTitle:七芍活血方治疗腰椎间盘突出症气滞血瘀证临床研究
- Author:
Yadi FENG
1
;
Shimin ZHANG
1
;
Guojun WANG
1
;
Jiao JIN
1
;
Hai LIN
1
;
Fudong SHI
1
;
Chun CHEN
1
Author Information
1. 中国中医科学院望京医院,北京 100020
- Publication Type:Journal Article
- Keywords:
lumbar disc herniation;
Qishao Huoxue Prescription;
qi stagnation and blood stasis syndrome;
hemorheology;
clinical efficacy
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(7):142-147
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Qishao Huoxue Prescription in treating low back pain caused by lumbar disc herniation with qi stagnation and blood stasis syndrome.Methods Totally 80 patients of lumbar disc herniation with qi stagnation and blood stasis syndrome were divided into observation group and control group according to random number table method,with 40 cases in each group.The observation group received oral administration of Qishao Huoxue Prescription,while the control group received oral celecoxib capsules for 3 weeks.Follow-ups were conducted after 1 month and 3 month of treatment,and the clinical efficacy of two groups after 3 months of treatment was evaluated.The Visual Analog Scale(VAS)scores,Japanese Orthopaedic Association Assessment of Treatment Score(JOA),Oswestry Disability Index(ODI)and Quality of Life(SF-36)scores for pain before treatment,1 and 3 weeks after treatment,and 1 and 3 months after treatment in two groups were observed;the blood flow changes of two groups before and after 3 weeks of treatment were observed,including whole blood high shear,medium shear,and low shear viscosity,plasma viscosity,and fibrinogen(FIB);adverse reactions in both group were recorded.Results The total effective rate in the observation group was 97.5%(39/40),significantly higher than 87.5%(35/40)in the control group(P<0.05).At 1 and 3 weeks of treatment and 1 and 3 months after treatment,VAS scores and ODI scores significantly decreased compared to before treatment,while JOA scores and SF-36 scores significantly increased in both groups.The improvement in scores in the observation group was better than that in the control group(P<0.01).The observation group showed a significant decrease in blood high,medium,and low shear viscosity,PV and FIB levels after 3 weeks of treatment compared to before treatment(P<0.05),and all levels were lower than those in the control group(P<0.05).No significant adverse reactions were observed in both groups.Conclusion Qishao Huoxue Prescription can significantly improve the clinical symptoms,hemorheological indicators,and quality of life of low back pain caused by lumbar disc herniation with qi stagnation and blood stasis syndrome,with good safety.
