Efficacy and safety of different thrombus removal methods for treatment of acute deep venous thrombosis of lower extremity
10.3969/j.issn.1002-1671.2025.05.027
- VernacularTitle:不同血栓清除方式治疗急性下肢深静脉血栓形成的疗效及安全性观察
- Author:
Xiaowei WANG
1
;
Shouzhong FU
1
;
Jiandong SHEN
1
;
Wei DING
1
;
Fengchen JIANG
1
;
Feng DAI
1
Author Information
1. 南通市第三人民医院 南通大学附属南通第三医院介入血管科,江苏 南通 226006
- Publication Type:Journal Article
- Keywords:
deep venous thrombosis;
AngioJet;
catheter thrombus aspiration;
catheter-directed thrombolysis
- From:
Journal of Practical Radiology
2025;41(5):840-844
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the short-term efficacy and safety of AngioJet mechanical thrombus removal,large lumen cathe-ter thrombus aspiration,and simple catheter-directed thrombolysis(CDT)for the treatment of acute deep venous thrombosis(DVT)of lower extremity.Methods A total of 75 patients with acute lower extremity DVT received interventional therapy were analyzed retrospectively,including 22 patients in AngioJet mechanical thrombus removal(group A),32 patients in large lumen catheter thrombus aspiration(group B),and 21 patients in simple CDT(group C).The short-term efficacy,health economics index,laboratory index and complications of the three groups were compared.Results The success rate of the three groups was 100％.Group A had superior thrombus clearance rates,lower dosages of urokinase,shorter thrombolysis durations,and shorter hospital stays compared to groups B and C.However,the hospitalization costs in group A were significantly higher than those in groups B and C,with statistically significant differences(P＜0.05).No significant renal dysfunction and severe complications were observed in the three groups.Post-operative creatinine levels in group A were higher than those in groups B and C,with statistically significant differences(P＜0.05).Both groups A and B experienced significant decreases in hematocrit postoperatively,and the absolute decrease and percentage decrease in hematocrit in group A were significantly greater than those in group C,with statistically significant differences(P＜0.05).Conclusion Compared to large lumen catheter thrombus aspiration and simple CDT treatment,AngioJet mechanical thrombus removal demonstrates higher efficiency in thrombus clearance rate but is associated with higher costs and risks of renal dysfunction.Postoperative care should focus on protecting renal function.
