Experimental Research Progress in TCM Compounds for the Prevention and Treatment of Tic Disorders
10.19879/j.cnki.1005-5304.202405541
- VernacularTitle:中药复方干预抽动障碍实验研究进展
- Author:
Jialin ZHONG
1
;
Maofu ZHANG
;
Lü GAO
;
Peng FENG
;
Jing SHANG
;
Zhenggang SHI
Author Information
1. 甘肃中医药大学,甘肃 兰州 730000
- Publication Type:Journal Article
- Keywords:
tic disorder;
Tourette syndrome;
TCM compound;
mechanism;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(7):192-196
- CountryChina
- Language:Chinese
-
Abstract:
Tic disorder is a chronic neuropsychiatric disorder with complex etiology and diverse phenotypes,and its incidence has been increasing significantly in recent years.Most scholars believe that abnormalities in the cortico-striatal-thalamo-cortical circuit and its interconnected brain regions are closely related to the development of tic disorder.Chinese materia medica intervention in tic disorders is characterized by multi-targets,multi-mechanisms and holistic nature,and has a good prospect for research application.This article summarized the experimental studies of TCM compound intervention in tic disorder in recent years,which have shown that TCM compounds could reduce the damage of nerve cells through the regulation of neurotransmitters,inflammatory response,immune function and the"colony-gut-brain axis"to improve and prevent tic disorder,which could provide a reference for the research and development of new medicines for tic disorder and for the clinical research.
