Analysis of the Current Status of Clinical Trial Registration for TCM in the Treatment of Psoriasis
10.19879/j.cnki.1005-5304.202407054
- VernacularTitle:中医药治疗银屑病临床试验注册现状分析
- Author:
Yiheng YANG
1
;
Zhan ZHANG
;
Biao LIANG
;
Shiwei QIAN
;
Jiachun NI
;
Shuo HUANG
;
Changpeng HAN
;
Zhenyi WANG
Author Information
1. 上海中医药大学附属岳阳中西医结合医院,上海 200437
- Publication Type:Journal Article
- Keywords:
psoriasis;
clinical trials;
Chinese Clinical Trial Registry;
TCM
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(7):67-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical trial projects of TCM treatment for psoriasis registered at the China Clinical Trial Registry(ChiCTR);To provide references for clinical research in this field.Methods Clinical trial studies on the TCM treatment for psoriasis were retrieved from the ChiCTR database from the establishment of the database to June 17,2024.Excel 2019 and GraphPad Prism 9.0 were used to organize and analyze the general characteristics included in registered clinical trials.Results Totally 65 TCM-related trials were included,of which 58(89.23%)were prospectively registered,and 55(84.62%)had undergone ethical review.The majority of trials were registered in Guangdong,Beijing and Shanghai,collectively accounting for 78.46%(n=51)of the total.The leading institution,Guangdong Provincial Hospital of Chinese Medicine,contributed 19 trials.Funding was predominantly sourced from governmental bodies,with 72.31%(n=47)supported by national or regional grants.Among the registered studies,interventional trials predominated(n=56),including 46 randomised parallel-controlled designs.Blinding was implemented in 23 trials,and biospecimen collection was reported in 48 studies.40 trials were single-centre studies,and a cumulative sample size was 17 695 participants.Common interventions included oral administration of classical TCM formulations or hospital-prepared remedies,alongside topical applications such as medicated baths and ointments.The primary outcome measure in most trials was the Psoriasis Area and Severity Index.Conclusion While the number of registered clinical trials on TCM for psoriasis in China demonstrates a fluctuating yet upward trend,the overall volume remains modest.Disparities in regional distribution,methodological variability,and incomplete trial registration details highlight areas for improvement.
