Exploration on the Medication Characteristics of Gu Shizhe in Treating Lumbar Disc Herniation Based on Data Mining
10.19879/j.cnki.1005-5304.202410058
- VernacularTitle:基于数据挖掘探讨谷世喆治疗腰椎间盘突出症用药特点
- Author:
Zhangjin MA
1
;
Hanbo MA
1
;
Feng CAO
1
;
Yongji YANG
1
;
Minglang XIE
1
;
Zhaoyang WANG
1
;
Shizhe GU
1
Author Information
1. 北京中医药大学针灸推拿学院,北京 100029
- Publication Type:Journal Article
- Keywords:
famous veteran TCM doctors;
Gu Shizhe;
lumbar disc herniation;
R language;
data mining;
association analysis
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(7):49-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the medication characteristics of Professor Gu Shizh in the treatment of lumbar disc herniation based on various data mining techniques.Methods The outpatient case records of Professor Gu was collected from January 2018 to September 2024 in the Guoyitang outpatient department of Beijing University of Chinese Medicine(BUCM)and BUCM Famous Elderly TCM Inheritance Research Integrated Platform.Patients with lumbar disc herniation mentioned in Professor Gu Shizhe's book of Zhi Zhen Zhi Yao were also be screened.R Studio 2024.4.3.2 was used for descriptive analysis and Apriori was used for association rule analysis.SPSS Statistics 27.0 was used for clustering analysis,and chiplot website was used for visualize the properties,tastes and meridians of drugs.Cytoscape 3.10.2 was used to build a network of"high frequency drug association",and combined with the TCM theories characteristics and medicine law used by professor Gu Shine in the treatment of lumbar disc herniation were summarized.Results A total of 63 cases were collected,involving 194 prescriptions and 187 kinds of Chinese materia medica.The top 30 drugs with the highest frequency were extracted,and the top 6 drugs were Angelicae Pubescentis Radix,Taxilii Herba,salt Eucommiae Cortex,Glycyrrhizae Radix et Rhizoma Praeparata cum Melle,Chuanxiong Rhizoma,Gentianae Macrophyllae Radix.The main tastes were sweet,bitter and pungent,the main properties were warm and neutral.The main meridians were liver,spleen,lung,kidney and stomach meridians.Three core medicinal combinations were obtained by clustering analysis,including Duhuo Jisheng Decoction,Gegeng Decoction,Zhijing Powder and Xuduan Pill.Conclusion The focus of Professor Gu's treatment for lumbar disc herniation is to nourish the liver and kidneys,warm and replenish qi and blood,reflecting the characteristics of"qi and blood are in harmony,essence and blood are equally emphasized"in medication
